Wilder Girls takes the essence of most YA sci-fi/dystopian novels and tightens the net around them. What's left is a small island in the Atlantic Ocean called Raxter Island. It's a school for girls that was doing relatively well on its own. Until the Tox hit. It affected each girl differently. Hetty's eye began bleeding, and she had to sew it shut. Byatt's spine warped and is now visible on her back, and Reese's hand has become a hardened silver. The Tox affected the adults differently, and most of them died shortly after it began. The younger girls weren't that affected until they hit puberty and the Tox spiked in them.